Understanding the nuances of gastrointestinal health requires differentiating between various medications. Proton Pump Inhibitors (PPIs), like Nexium, function by reducing stomach acid production, a key distinction from antacids that neutralize existing acid. This article explores the core question: is nexium an antacid? We will delve into the mechanism of action for both, considering the insights from organizations such as the FDA (Food and Drug Administration) that regulate these pharmaceutical products. Grasping the difference between these two medication classes is vital for informed healthcare decisions.

Image taken from the YouTube channel Consumer Reports , from the video titled Nexium overuse | Consumer Reports .
Heartburn, acid reflux, and indigestion are common ailments affecting millions. Navigating the world of over-the-counter and prescription medications aimed at alleviating these symptoms can be confusing. Two prominent types of medications often come up in discussions about acid-related issues: Nexium and antacids.
But are they the same? This is a crucial question to answer for effective symptom management and overall digestive health.
What is Nexium?
Nexium, also known by its generic name esomeprazole, is a prescription medication belonging to a class of drugs called proton pump inhibitors (PPIs). PPIs work by reducing the amount of acid produced in the stomach.
This reduction in acid helps to relieve symptoms associated with conditions like gastroesophageal reflux disease (GERD), esophagitis (inflammation of the esophagus), and stomach ulcers. Nexium is a powerful medication that can provide significant relief for individuals suffering from chronic acid-related problems.
What are Antacids?
Antacids, on the other hand, are typically over-the-counter medications designed to provide quick, temporary relief from heartburn and indigestion. They work by neutralizing stomach acid, essentially buffering the acid and making it less irritating to the esophagus.
Common examples of antacids include Tums, Rolaids, and Maalox. While antacids can be effective for occasional heartburn, they do not address the underlying cause of acid reflux or prevent the stomach from producing excess acid in the long run.
The Key Question: Is Nexium an Antacid?
The central question we aim to address is: Is Nexium an antacid? The short answer is no. While both Nexium and antacids are used to manage acid-related symptoms, they work through different mechanisms and are intended for different purposes.
Nexium, as a PPI, targets the production of stomach acid, while antacids neutralize the acid that has already been produced. This fundamental difference has significant implications for how and when these medications should be used.
Why Understanding the Difference Matters
Understanding the difference between Nexium and antacids is essential for several reasons. First, it ensures that individuals are using the appropriate medication for their specific condition.
Second, it helps to manage expectations regarding the duration and effectiveness of each treatment.
Finally, it highlights the importance of seeking professional medical advice for persistent or severe acid reflux symptoms, as these could indicate an underlying condition requiring more comprehensive treatment than antacids alone can provide.
The central question we aim to address is: Is Nexium an antacid? The short answer is no. While both Nexium and antacids are used to alleviate acid-related discomfort, their mechanisms of action, effectiveness, and appropriate uses differ significantly. Let’s dive deeper into the world of antacids to understand their role in managing heartburn and acid reflux.
Understanding Antacids: Quick Relief, Limited Power
Antacids are a staple in many medicine cabinets, readily available over-the-counter for fast relief from heartburn and indigestion. Their accessibility and quick action make them a popular choice for occasional discomfort. However, it’s crucial to understand how they work and what their limitations are to use them effectively.
The Neutralizing Power of Antacids
At their core, antacids are basic (alkaline) substances that work by neutralizing the hydrochloric acid produced in the stomach. This neutralization increases the stomach’s pH level, making it less acidic.
This, in turn, reduces the irritation to the esophagus and provides temporary relief from the burning sensation associated with heartburn. Think of it like adding baking soda to vinegar – the reaction reduces the overall acidity of the mixture.
When Antacids Shine: Treating Occasional Heartburn
The primary use of antacids is to alleviate occasional heartburn and indigestion. After a particularly rich or spicy meal, or when experiencing mild acid reflux, antacids can provide quick relief.
They are particularly useful for individuals who experience infrequent heartburn triggered by specific dietary or lifestyle factors. For instance, someone who occasionally gets heartburn after drinking coffee might find relief with an antacid.
However, they are not designed to address chronic or persistent acid-related issues.
The Limitations of Quick Relief
While antacids offer fast relief, their effects are relatively short-lived. The neutralization of stomach acid is a temporary fix, and the stomach will continue to produce acid.
This means that the symptoms may return as the antacid is cleared from the system. Furthermore, antacids only address the symptoms of acid reflux; they do not heal any existing damage to the esophagus caused by chronic acid exposure.
Antacids do not prevent acid production. They only neutralize existing acid. This is a crucial distinction from medications like Nexium, which actively reduce acid production.
Masking the Problem, Not Solving It
Relying solely on antacids for persistent heartburn can mask underlying problems. If heartburn is frequent or severe, it could be a sign of a more serious condition like gastroesophageal reflux disease (GERD) or esophagitis.
In these cases, simply neutralizing the acid will not address the root cause and could delay proper diagnosis and treatment. It’s essential to consult a doctor if antacids are needed frequently or if they don’t provide adequate relief.
Popular Over-the-Counter Antacid Brands
The market is flooded with various antacid brands, each containing different active ingredients. Some of the most common over-the-counter (OTC) antacid brands include:
- Tums: Contains calcium carbonate as its active ingredient.
- Rolaids: Typically contains calcium carbonate and magnesium hydroxide.
- Maalox: Often contains aluminum hydroxide and magnesium hydroxide.
- Mylanta: Similar to Maalox, containing aluminum hydroxide and magnesium hydroxide, and sometimes simethicone to relieve gas.
While these brands may differ slightly in their formulations, they all share the same core mechanism of action: neutralizing stomach acid for temporary relief.
The use of antacids offers immediate relief by directly neutralizing stomach acid, however, their effect is short-lived and doesn’t address the root cause of excessive acid production. For those experiencing frequent or severe acid-related issues, a different approach is needed.
Nexium: A Proton Pump Inhibitor (PPI) with a Different Approach
Unlike antacids that merely neutralize existing acid, Nexium, as a proton pump inhibitor (PPI), tackles the problem at its source: acid production. This distinction is critical in understanding why Nexium is prescribed for different conditions and offers a longer-lasting solution for many.
Understanding Proton Pump Inhibitors (PPIs)
PPIs represent a class of medications that work by specifically targeting and inhibiting the proton pumps in the stomach lining. These pumps are responsible for secreting hydrochloric acid, the very acid that causes heartburn and other related issues.
By blocking these pumps, PPIs effectively reduce the amount of acid the stomach produces.
This mechanism differs drastically from antacids, which only neutralize the acid already present.
Nexium’s Mechanism: Targeting Acid Production at the Source
Nexium, containing the active ingredient esomeprazole, is a prime example of a PPI. It works by irreversibly binding to the proton pumps in the stomach lining.
This action directly inhibits their ability to secrete acid.
The effect is a significant and sustained reduction in stomach acid production.
This reduction creates a less acidic environment in the stomach. This provides relief from symptoms and allows damaged tissues in the esophagus and stomach to heal.
Conditions Commonly Treated with Nexium
Nexium is typically prescribed for conditions characterized by excessive stomach acid production or damage to the esophagus.
Gastroesophageal reflux disease (GERD) is a common condition treated with Nexium. GERD occurs when stomach acid frequently flows back into the esophagus, causing heartburn and other symptoms.
Esophagitis, or inflammation of the esophagus, is another condition often treated with Nexium. It helps to reduce further irritation and allows the esophagus to heal.
Ulcers, both gastric (stomach) and duodenal (small intestine), can also be treated with Nexium. Reducing stomach acid helps prevent further erosion of the ulcer and promotes healing.
In some cases, Nexium may be used in combination with antibiotics to treat ulcers caused by Helicobacter pylori (H. pylori), a bacteria that can infect the stomach lining.
Longer Duration of Action Compared to Antacids
One of the key differences between Nexium and antacids is the duration of their effects. Antacids provide quick but temporary relief, lasting only a few hours at most.
Nexium, on the other hand, offers a longer duration of action.
Its effects can last for up to 24 hours or more, providing sustained acid control throughout the day and night.
This longer duration is due to its mechanism of action – inhibiting acid production rather than simply neutralizing existing acid.
Because PPIs work by inhibiting the proton pumps, it takes time for the body to produce new pumps. This further extends the duration of acid suppression.
The contrasting approaches of antacids and Nexium become even clearer when directly compared. Understanding these distinctions is crucial for making informed decisions about managing acid-related conditions.
Nexium vs. Antacids: A Side-by-Side Comparison
To fully grasp the difference between Nexium and antacids, let’s examine their key characteristics side-by-side. This comparison will cover how they work, what they’re used for, how long they last, how quickly they provide relief, and their potential side effects.
Mechanism of Action: Neutralizing vs. Inhibiting
The fundamental difference lies in how each medication addresses stomach acid.
Antacids act as neutralizers, directly counteracting the acid already present in the stomach. Think of them as a temporary mop for a spill.
Nexium, on the other hand, is a proton pump inhibitor (PPI). It functions like turning off the faucet, reducing acid production at its source.
Uses: Occasional Relief vs. Chronic Management
Antacids are best suited for occasional heartburn or acid indigestion. They provide quick relief for sporadic symptoms.
Nexium is typically prescribed for chronic conditions like GERD (gastroesophageal reflux disease), esophagitis (inflammation of the esophagus), and stomach ulcers. These conditions require sustained acid control for healing and symptom management.
Duration of Action: Short-Term vs. Long-Lasting
Antacids offer relatively short-lived relief, usually lasting for a couple of hours.
Their effects diminish as the stomach produces more acid.
Nexium provides a longer duration of action, typically lasting for up to 24 hours. This sustained effect is due to its impact on acid production, rather than simply neutralizing existing acid.
Time to Onset of Relief: Immediate vs. Gradual
Antacids offer immediate relief, as they directly neutralize stomach acid. This makes them ideal for quick symptom control.
Nexium takes longer to provide relief, usually within 1 to 4 days. This is because it needs time to reduce acid production effectively. It is not designed for immediate relief.
Potential Side Effects: A Spectrum of Possibilities
Antacids can cause side effects like constipation or diarrhea, especially with overuse. Some formulations can also interfere with the absorption of certain medications.
Nexium, like all PPIs, carries a risk of more significant side effects, especially with long-term use. These can include nutrient deficiencies (e.g., vitamin B12, magnesium), increased risk of certain infections (e.g., C. difficile), and potentially bone fractures. It is important to remember these risks are typically associated with long-term use and should be discussed with a healthcare professional.
Summarizing the Key Differences
Feature | Antacids | Nexium (PPI) |
---|---|---|
Mechanism | Neutralizes existing stomach acid | Inhibits stomach acid production at the source |
Uses | Occasional heartburn, acid indigestion | Chronic GERD, esophagitis, ulcers |
Duration | Short (1-2 hours) | Long (up to 24 hours) |
Onset | Immediate | Gradual (1-4 days) |
Side Effects | Constipation, diarrhea, drug interactions | Nutrient deficiencies, infection risk |
Clarifying the Misconception: Nexium is a PPI, Not an Antacid
It’s crucial to reiterate: Nexium is NOT an antacid. It belongs to a different class of medications called proton pump inhibitors (PPIs). Understanding this distinction is essential for appropriate treatment and management of acid-related conditions.
Nexium provides a different approach, targeting acid production at its source for more sustained relief. But how do you know which option is right for you? Understanding the specific scenarios where each medication shines is key to managing your symptoms effectively.
When to Use Antacids vs. When to Consider Nexium (or other PPIs)
Knowing when to reach for an antacid versus when to seek professional medical advice for a prescription medication like Nexium is essential for effective and safe management of acid-related issues.
Antacids: Your Go-To for Occasional Relief
Antacids are a great option for quick, temporary relief of mild heartburn or indigestion. Think of that uncomfortable burning sensation after a particularly rich meal.
These over-the-counter medications can neutralize the excess acid, providing relief within minutes.
They are best suited for those infrequent episodes of discomfort. They are not designed to address the underlying causes of chronic acid reflux.
Common scenarios where antacids may be sufficient include:
- After eating a large meal.
- Following consumption of known trigger foods.
- Experiencing occasional heartburn related to stress.
When to Consult a Doctor: Recognizing the Need for Stronger Intervention
While antacids can provide relief for occasional heartburn, certain situations warrant a visit to your doctor.
Ignoring persistent symptoms or self-treating with over-the-counter medications for extended periods can mask underlying issues and delay appropriate diagnosis and treatment.
Here are some key indicators that it’s time to seek professional medical advice:
Frequent or Severe Heartburn
If you experience heartburn more than twice a week, it may be a sign of a more serious condition like GERD.
Severe heartburn that significantly impacts your daily life also requires evaluation.
Symptoms Not Relieved by Antacids
When antacids fail to provide adequate relief, or the relief is short-lived, it’s time to consult a healthcare professional. This suggests that the problem goes beyond simple acid indigestion.
Suspected GERD or Other Underlying Conditions
If you suspect you have GERD (Gastroesophageal Reflux Disease) or another underlying condition, such as esophagitis or a hiatal hernia, it is important to seek a diagnosis.
Early diagnosis and management can prevent complications.
Symptoms suggestive of GERD include:
- Persistent heartburn.
- Regurgitation of food or sour liquid.
- Difficulty swallowing.
- Chronic cough or sore throat.
Need for Long-Term Acid Control
If you find yourself relying on antacids frequently for symptom control, it indicates a need for a more sustainable solution.
Long-term use of antacids can have side effects and may not address the root cause of your symptoms. A doctor can assess your condition. They can recommend a more appropriate long-term management plan, potentially involving a PPI like Nexium or other treatments.
The Importance of Medical Supervision with PPIs
It’s crucial to understand that while PPIs like Nexium are effective for managing acid-related conditions, they are not intended for long-term, unsupervised use.
Self-treating with PPIs for extended periods without consulting a doctor can carry risks.
Long-term PPI use has been associated with potential side effects. These may include:
- Nutrient deficiencies (e.g., vitamin B12, magnesium).
- Increased risk of certain infections (e.g., C. difficile).
- Potential bone fractures.
A doctor can assess your individual needs, weigh the benefits and risks of PPI therapy, and monitor you for any potential side effects.
They can also explore alternative treatments and lifestyle modifications. They can help you manage your condition effectively and safely.
Knowing when to reach for an antacid and when to consider something stronger like Nexium is a great first step, but understanding the full picture also means being aware of potential downsides. Let’s take a closer look at the side effects and long-term considerations associated with Nexium use.
Potential Side Effects and Long-Term Considerations of Nexium
While Nexium can be a highly effective medication for managing acid-related conditions, it’s important to be aware of its potential side effects and the considerations that come with long-term use. Like all medications, Nexium carries a risk of adverse effects, and understanding these risks is crucial for making informed decisions about your health.
Common Side Effects of Nexium
Many individuals who take Nexium experience few or no side effects. However, some common side effects can occur, which are generally mild and temporary.
These can include:
- Headache
- Diarrhea
- Nausea
- Flatulence
- Abdominal pain
- Dry mouth
If any of these side effects become bothersome or persistent, it’s important to consult with your doctor.
Potential Risks Associated with Long-Term PPI Use
Long-term use of Proton Pump Inhibitors (PPIs) like Nexium has been linked to several potential risks. While these risks are relatively rare, they are important to consider, especially if you’ve been taking Nexium for an extended period.
Nutrient Deficiencies
PPIs can interfere with the absorption of certain nutrients, potentially leading to deficiencies over time.
These include:
- Vitamin B12: Reduced stomach acid can impair the absorption of vitamin B12, potentially leading to neurological problems and anemia.
- Magnesium: PPIs can decrease magnesium absorption, which can cause muscle cramps, fatigue, and irregular heartbeats.
- Calcium: Some studies suggest a link between long-term PPI use and an increased risk of fractures, possibly due to impaired calcium absorption.
- Iron: Insufficient iron may result in decreased red blood cell production and reduced oxygen transport.
Increased Risk of Certain Infections
The reduction of stomach acid caused by PPIs can potentially increase the risk of certain infections.
This is because stomach acid plays a role in killing harmful bacteria that enter the body through food and water.
- Clostridium difficile (C. diff) Infection: Studies have linked PPI use to an increased risk of C. diff infection, a severe diarrheal illness.
- Pneumonia: Some research suggests a slightly elevated risk of pneumonia in PPI users, possibly due to changes in the gut microbiome.
Other Potential Concerns
While research is ongoing, some studies have also suggested potential links between long-term PPI use and other health issues.
This includes chronic kidney disease and an increased risk of developing stomach polyps.
Minimizing Risks: Dosage and Duration
To minimize the potential risks associated with Nexium, it’s crucial to use the medication at the lowest effective dose for the shortest possible duration. Work closely with your doctor to determine the appropriate dosage and treatment plan for your specific condition.
Avoid self-treating with PPIs long-term without medical supervision. Regular monitoring and assessment can help identify and address any potential side effects or complications early on.
Discussing Concerns with Your Doctor
The information provided here is not a substitute for professional medical advice. If you have any concerns about the side effects or long-term risks of Nexium, it’s essential to discuss them with your doctor.
They can assess your individual risk factors, monitor your health, and adjust your treatment plan as needed.
Don’t hesitate to ask questions and seek clarification on any aspects of your medication that you don’t fully understand. Your doctor is your partner in managing your health, and open communication is key to achieving the best possible outcomes.
Knowing when to reach for an antacid and when to consider something stronger like Nexium is a great first step, but understanding the full picture also means being aware of potential downsides. Let’s take a closer look at the side effects and long-term considerations associated with Nexium use. Even with the best medical interventions, however, managing acid reflux often requires a multi-faceted approach. Medication can provide significant relief, but lasting control frequently hinges on incorporating meaningful lifestyle and dietary adjustments.
Lifestyle and Dietary Changes for Acid Reflux Management
Medications like Nexium address acid reflux by reducing acid production, but they don’t address the underlying lifestyle factors that can contribute to the problem. Implementing strategic changes in your daily routine and dietary choices can significantly reduce symptoms, enhance the effectiveness of medication, and potentially even decrease your reliance on it.
The Power of Lifestyle Adjustments
Simple yet powerful lifestyle modifications can have a profound impact on acid reflux.
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Elevating the Head of Your Bed: This is one of the most frequently recommended strategies. By raising the head of your bed by 6-8 inches, you can use gravity to your advantage, preventing stomach acid from flowing back into the esophagus while you sleep. This can be achieved with bed risers or a wedge pillow.
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Timing Your Meals: Avoid eating large meals, especially close to bedtime. Give your stomach ample time to digest food before lying down. Aim to finish your last meal at least 2-3 hours before going to sleep.
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Quitting Smoking: Smoking weakens the lower esophageal sphincter (LES), the muscle that prevents stomach acid from backing up into the esophagus. Quitting smoking can significantly improve LES function and reduce acid reflux.
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Maintaining a Healthy Weight: Excess weight, especially around the abdomen, can put pressure on the stomach, increasing the risk of acid reflux. Losing weight through a balanced diet and regular exercise can alleviate this pressure.
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Mindful Eating Habits: Eating slowly and chewing your food thoroughly can aid digestion and reduce the likelihood of acid reflux.
Decoding Dietary Triggers
Certain foods and beverages are notorious for triggering acid reflux. Identifying your personal triggers and making adjustments to your diet can make a significant difference in symptom management.
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Common Culprits:
- Caffeine: Coffee, tea, and energy drinks can relax the LES, increasing the risk of acid reflux.
- Alcohol: Similar to caffeine, alcohol can also weaken the LES and irritate the esophageal lining.
- Spicy Foods: Spicy foods can irritate the esophagus and stimulate acid production.
- Fatty Foods: Fatty foods take longer to digest, which can lead to increased stomach pressure and acid reflux.
- Citrus Fruits and Juices: These can be highly acidic and irritate the esophagus.
- Chocolate: Chocolate contains methylxanthines, which can relax the LES.
- Carbonated Beverages: These can increase stomach pressure and contribute to acid reflux.
- The Elimination Diet Approach: A useful strategy is to keep a food diary and eliminate suspected trigger foods one at a time to see if your symptoms improve. This helps you pinpoint your individual sensitivities.
The Synergistic Effect: Combining Lifestyle, Diet, and Medication
While medication can provide relief, lifestyle and dietary modifications address the root causes of acid reflux, creating a synergistic effect. These changes can:
- Reduce the frequency and severity of acid reflux episodes.
- Enhance the effectiveness of medications like Nexium.
- Potentially decrease the need for long-term medication use, minimizing the risk of side effects.
- Improve overall digestive health and well-being.
Ultimately, managing acid reflux is a collaborative effort between you and your healthcare provider. While medication plays a role, don’t underestimate the power of lifestyle and dietary changes in achieving long-term relief and improving your quality of life.
Diagnosis and Treatment of Underlying Conditions: When to See a Doctor
Medications and lifestyle adjustments can often manage acid reflux symptoms effectively. However, persistent or severe heartburn warrants a visit to your healthcare provider. Lingering symptoms could signal an underlying condition requiring specific diagnosis and treatment. Ignoring these warning signs could lead to complications and delay appropriate care.
Recognizing When Self-Care Isn’t Enough
Occasional heartburn, often triggered by specific foods or habits, can usually be managed with over-the-counter antacids and lifestyle modifications. But what constitutes "persistent" or "severe" heartburn?
If you experience heartburn more than twice a week, despite dietary and lifestyle changes, it’s time to consult a doctor. Similarly, if your symptoms worsen over time or do not respond to over-the-counter medications, seeking medical attention is crucial.
The Importance of Medical Evaluation
Recurring or intense acid reflux can be a symptom of more serious underlying conditions, including:
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Gastroesophageal Reflux Disease (GERD): A chronic condition where stomach acid frequently flows back into the esophagus, irritating its lining.
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Esophagitis: Inflammation of the esophagus, often caused by acid reflux.
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Barrett’s Esophagus: A precancerous condition where the lining of the esophagus changes due to chronic acid exposure.
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Hiatal Hernia: A condition where part of the stomach protrudes through the diaphragm.
Only a qualified healthcare professional can accurately diagnose these conditions. Self-treating with over-the-counter remedies may mask the symptoms without addressing the root cause.
Potential Diagnostic Tests
Your doctor may recommend one or more diagnostic tests to determine the cause and extent of your acid reflux. Some common tests include:
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Endoscopy: A procedure where a thin, flexible tube with a camera is inserted into the esophagus to visualize its lining and detect any abnormalities.
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Esophageal pH Monitoring: A test that measures the amount of acid in the esophagus over a period of time, typically 24 hours.
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Esophageal Manometry: A test that measures the pressure and coordination of muscle contractions in the esophagus.
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Barium Swallow: An X-ray procedure that uses a contrast liquid to visualize the esophagus and stomach.
The choice of diagnostic test depends on your individual symptoms and medical history. Discuss your concerns and medical history openly with your doctor.
Personalized Treatment Plans are Essential
The treatment approach for acid reflux should be tailored to the individual patient and the underlying cause of their symptoms. While medications like PPIs (e.g., Nexium) can be effective in reducing acid production, they may not be the only solution.
Depending on the diagnosis, your doctor may recommend a combination of:
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Medication: PPIs, H2 blockers, or prokinetics to manage acid production and improve esophageal function.
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Lifestyle Modifications: Continued adherence to dietary and lifestyle changes to minimize reflux triggers.
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Surgery: In severe cases, surgery may be necessary to repair a hiatal hernia or strengthen the lower esophageal sphincter.
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Alternative Therapies: In some cases, practitioners use various alternative treatments. The efficacy and safety of these treatment approaches vary widely.
It is essential to remember that one size does not fit all when it comes to acid reflux treatment. Working closely with your doctor is critical to develop a personalized plan that effectively manages your symptoms and addresses the underlying cause.
FAQs: Nexium – Antacid or Something More?
Here are some frequently asked questions to help clear up any confusion about Nexium and its uses.
What exactly is Nexium and what does it treat?
Nexium is a proton pump inhibitor (PPI), a type of medication that reduces stomach acid production. It’s prescribed for conditions like GERD (gastroesophageal reflux disease), ulcers, and erosive esophagitis. It works by targeting the cells in your stomach that produce acid.
So, is Nexium an antacid?
No, Nexium is not an antacid. Antacids, like Tums or Rolaids, neutralize stomach acid that’s already present, providing quick but temporary relief. Nexium, on the other hand, reduces the production of stomach acid, offering longer-lasting relief.
How long does it take for Nexium to start working?
While antacids provide immediate relief, Nexium takes longer to become effective. It can take one to four days of consistent use for Nexium to fully reduce stomach acid production and alleviate symptoms.
What are some potential side effects of taking Nexium?
Common side effects of Nexium can include headache, diarrhea, nausea, gas, and constipation. Although rare, more serious side effects can occur, so it’s essential to discuss any concerns with your doctor. If you’re unsure if is nexium an antacid or not, it’s best to seek clarification from a healthcare professional.
Hopefully, this clarified everything about whether is nexium an antacid! Always chat with your doctor about your specific needs, okay? Take care!